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Medicine that inhibit CYP2D6 action, like paroxetine and quinidine, might result in decreased clearance of oxycodone which may lead to an increase in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in an increase in oxycodone Cmax by eleven%, AUC by thirteen%, and t½ elim.Likewise to most other opioids, oxycodone i

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